Clearin’ of the Links: Science, Technology, and Medicine Chum

userpic=mad-scientistI’m still working on clearing out the links that accumulated during the Hollywood Fringe Festival (FB), with a goal of getting them all done before you take off for the Fourth of July weekend. I may already be too late. Here’s a chunk that are loosely related to science, medicine, and technology:

Medicine Chum

  • Understanding Migraines. One of the ills that plague me are migraines (which, luckily for me, are mild compared to what others get). No one knows precisely what triggers migraines, or how the various abortives work. Some think it is related to nerves in the head, and some think it is related to blood flow.  A new genome-wide association study published in Nature Genetics suggests that a migraine may primarily stem from problems with the blood supply system. This could lead to new ways to treat migraines.
  • More Than Human. We’re discovering more and more than the human organism is much more than the human organism — that is, much of what contributes to our health or lack thereof is our microbiome. Further, our overfocus on being “germ-free” has significantly hurt our biome, and may be the single largest contributor to our various health maladies — including obesity. Here’s another biome story — this time, the involvement of the biome with what has been called Chronic Fatigue Syndrome. Specifcally, researchers say they’ve found biological markers of the illness in the blood and gut bacteria of people with systemic exertional intolerance disease (SEID) (a/k/a CFS). Their results were published in the journal Microbiome. In this study, found clear differences between the blood and guts of healthy versus sick people. Compared to healthy controls, people with ME/CFS had weaker and less diverse bacterial ecosystems in their guts, as well as higher levels of immune inflammation in their blood. These differences were so clear that the researchers were able to spot nearly 83 percent of the time which participants had ME/CFS just by looking at their bacterial and immune response results.
  • Being Like Everyone Else. If everyone else did something with no proven medical benefit for medical reasons (like, for example, overusing bacterial soap), would you do it? A study that is unsurprisingly proving very viral on social networks is highlighting one such thing: most women these days are “preparing for the Olympics” for claimed medical benefit, when there is none (where “preparing for the Olympics” == “going Brazilian” == removing hair on their … == insert your own euphemism here). My attitude, for whatever it is worth, is that women are their most beautiful when they look like women — not airbrushed models or pre-pubescent girls — but women – with imperfections and hair and some parts large and some parts small and some parts inbetween. While we’re on that subject (and while we’re clearing links), here’s an article I found on two-piece suits for large chested ladies. What bothered me about that article is that the chest was the only part that was large. Why weren’t there two-pieces for ladies who happened to be large in other places as well? As it is, an article like that is just perpetuating body dismorphic ideas, just like shaving everywhere does.
  • How Old is Your Body? I’m 56. Recently, I’ve been wondering if there is any part of my body that has been with me all 56 years. So I was quite pleased to see an article come across my feeds that asked the same question: How old is your body? What component of your body has been around the longest time? For example: brand new fingernails every six months, 2-7 years for the hair on our heads, new skeletal muscles every 15 years. But those neurons in your brain? Never replaced.

Technology Chum

  • Automotive Security. We were having a discussion on our van this morning about car security, specifically how some thieves are collecting automotive RFID signals, and then going around parking lots broadcasting them, unlocking cars, and stealing stuff inside. I had noted how cars are generally better protected against theft, and how entertainment units are less likely to be stolen than radios of old. Another rider pointed out, however, that the keyless ignition cars are easier to steal. In general, our cars are weak in terms of security — so it is good at the Senator is pushing to increase cybersecurity protections in cars.
  • LED Streetlight Dangers. More and more cities are going to LED streetlights because they use less energy and are brighter. Now the AMA has come out with some cautions on LED lighting: cool it and dim it. The AMA’s statement recommends that outdoor lighting at night, particularly street lighting, should have a color temperature of no greater than 3000 Kelvin (K). Color temperature (CT) is a measure of the spectral content of light from a source; how much blue, green, yellow and red there is in it. A higher CT rating generally means greater blue content, and the whiter the light appears. The new “white” LED street lighting which is rapidly being retrofitted in cities throughout the country has two problems, according to the AMA. The first is discomfort and glare. Because LED light is so concentrated and has high blue content, it can cause severe glare, resulting in pupillary constriction in the eyes. Blue light scatters more in the human eye than the longer wavelengths of yellow and red, and sufficient levels can damage the retina. This can cause problems seeing clearly for safe driving or walking at night. It can also affect our sleep cycles and rhythms (which is why many people recommend using f.lux to turn down the blue on your screens in the evening).
  • Tweaking Your Facebook Feed. Many of us who came from LJ miss the days of a sequential feed, where you know you could catch up on your friends. Facebook has never been quite the same. But Facebook is now providing some details on how to tweak your feed. First, they’ve disclosed their news feed algorithm, which will now show posts from friends higher up in the feed than posts from Pages like news outlets. Based on these new values, there are now some specific tweaks that you can do to make your newsfeed what you want it to be.

Science Chum

Science People In the News

  • New Position: Steve Isakowitz. The Aerospace Corporation (my employer) has announced the selection of a new corporate President and soon-to-be CEO: Steve Isakowitz, former President of Virgin Galactic. Iskowitz is also a former CTO of Virgin Galactic. Previously, he held a wide variety of senior engineering, business, and management roles across the private and government sectors, including positions at NASA, the Office of Management and Budget, the Intelligence Community, and the Department of Energy. He replaces Wanda Austin, who has reached the corporate age limit for VPs and above.
  • Passing: Simon Ramo. Simon Ramo, the “R” in TRW, has passed away.  Ramo shaped California aerospace and the space industry through organizations like TRW, and I should note that he is responsible for the company I work at: The Aerospace Corporation is actually an FFRDC spin-off of STL, Space Technology Laboratories, which went on to become TRW.
  • Passing: Steve Walker. Word came to me Thursday morning of the passing of Steve Walker, one of the seminal people in the field of cybersecurity. The formal obituary and funeral arrangements haven’t been published; I found a bio here. We’ll get something up on the ACSA In Memorium page as soon as we can.

 

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Week End News Chum: Threading a Connection

Observation StewFor some, this is the start of a 3 day weekend; for others, just the normal weekend craziness. Whichever it is, it’s been a busy week. I’ve been accumulating a lot of articles of interest, but none of them have themed into groups of three, or proved to be the start of a single-subject rant. So let’s toss them into the crock-pot of discussion, and see if we can at least come up with a thread to connect each to the next:

Lastly, I’m sure you think I’m crazy in the head for trying to thread all these disparate articles together. Speaking of crazy in the head: how’s this for a headline: “Doctors dismissed his pain as migraines. Then they said he had 24 hours to live.” Did that get your attention? It got mine. The connected article was about something I mentioned last week: undetected subdural hematomas. Scary.

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It’s What’s For Dinner: Mixed-Up News Chum Stew

Observation StewFinally, it is time for the main dish: A hearty news chum stew made up of items that I just couldn’t form up into a coherent (or even incoherent) post. I’ll note the first three are roughly science related:

  • Things That Go Bump in the … Ouch. The title is worrisome enough on its own: “How A Simple Bump Can Cause An Insidious Brain Injury“. The concern here is a kind of brain injury that’s very insidious — a subdural hematoma. These don’t occur with falling off a ladder, slipping and bash your head on the ice, or playing football. Basically — and this can be a problem as you get older — you bump your head. You get a small brain bleed, but below the dura that lines the brain. The bleed creates a very low-pressure ribbon of blood that’s layering on top of the surface of the brain. As that blood starts to pool over days or weeks, it irritates the brain cells. And if the pool’s big enough, it presses on the brain and damages it, much like a tumor. Ouch.
  • It’s better than Progenitorivox. Asprin is indeed a miracle drug, when taken daily. Not only can it help your heart, but it can lower your risk of prostate disease. Men with prostate cancer had almost a 40% lower risk of dying of the disease if they were taking aspirin for cardiovascular protection, a large cohort study showed.
  • At Last My Row Is Complete Again. Those of you with real periodic tables of wood, time to get out your engraving router. The last row of the periodic table has been filled: the final four elements are confirmed. Needless to say, you won’t be able to keep the samples for long. That’s how it goes.
  • Clearing Out the Stash. Lots of useful info here for knitters and crocheters. Here is a list of 10 charities looking for yarn projects, and in that list are links to about 15 more. There’s also Operation Gratitude, which is looking for knitted scarfs for soldiers. Now, go forth and clean out that sewing room. Your non-crafting partners will thank you.
  • High Fashion Religious Scarfs. A couple of related items here. First, Dolce & Gabbana have launched a line of high-fashion hijabs and abaysas (Islamic head scarves). This is actually a big deal, as the purchasing power of this market is high, and this is an untapped area of fashion. In a different religious area, H&M has marketed a scarf that looks very much like a tallit.  This is a bit more in bad taste (although I must admit we once did find a fancy tallit in a thrift store — National Council of Jewish Women, in fact — that was labeled as a scarf). It is so problematic that they have pulled it from sale in Israel.  Just imagine the next conversation: Hey, boss: I’ve got this great idea for a new hat for women.
  • Tongue Tied. Moving from the Hebrew to the Yiddish: Here is a set of Yiddish Tongue Twisters. My favorite? “Schmoozing in the shtetl with a schmutzy sheitel is a shande.”
  • Ikea Games. Mental Floss had a neat article on secrets of Ikea. One is that there are multiple quick routes through the store, both for safety reasons and stocking reasons, and they’re open to the public. But they’re not advertised, so you’ll need a keen eye for secret passageways. Often they take the form of unmarked service doors. But they change them fairly frequently because customers get familiar with the shortcuts and know how to zip through. They change the shortcuts to force people to go around the long way again.
  • Getting a Lyft. I’ve been hearing more and more about Lyft and Uber. I’ve never used them. In LA, Lyft has just been authorized to pick up at LAX. Here’s a report on what it is like to use Lyft at LAX.
  • Ride the Red Cars. It is appropriate that I’m wearing an Orange Empire shirt as I type this. Here’s a retrospective on the decline of the Pacific Electric in Los Angeles. Alas, as usual, the comments go off the rail into conspiracy theories and partisan politics (yes, the removal of PE is Obama’s fault. Right.). Further, no one mentions they are still running at OERM.
  • There are Beans, and there are Beans. The inventor of Jelly Bellies is jonesing for a comeback. His next idea: caffeinated coffee jelly beans. Now that his non-compete has passed, the founder and his business partners have launched a Kickstarter campaign seeking $10,000 to launch their Original Coffee House Beans, which will come in flavors such as hot cocoa and peppermint, chai tea, coffee and doughnuts and caffe macchiato. Sounds interesting. Sugar and caffeine in one little pill. Who needs an energy drink.

 

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Science and Health News Chum: Detecting Gluten, Medicine Notes, Sex, Plastic, and Love

userpic=mad-scientistAs I noted in my highway headline post, it’s been very busy around here. Still, I’ve collected a few articles of interest. This collection is all connected by being related to recent science and health discoveries:

  • Detecting Gluten. One article I read recently led me to discover a handheld sensor about to hit the market: the Nima sensor. Nima, is a portable, handheld gluten detector. Users load a half-teaspoon sample of food into a test tube and pop that into a triangle-shaped sensor. (They’ll need to use a new disposable capsule for each test to avoid cross-contamination.) The sensor assesses the contents of the capsule—detecting trace elements of gluten down to 20 parts per million—and then spits out a “yes” or “no” within two minutes. “No” signals that the food is safe to eat; a “yes” indicates that gluten is present. We’ve added ourselves to the mailing list for more info.
  • Generic Medicines. Recently, I was prescribed a blood pressure medicine that was almost $100 after insurance (I’ve since switched to a generic that is much cheaper). With that experience, the problem with the pricing of generics was on my mind — and so this article on the pricing of generic medicines caught my eye. Part of the problem is bioequivalence studies. Generic drugs don’t need the excruciatingly drawn-out safety and efficacy studies required of new brand-name medications, but they do need to pass a bioequivalency study proving that their drug is absorbed the same way as the original. According to Wikipedia, the most common type of bioequivalence study is to “measure the time it takes the generic drug to reach the bloodstream in 24 to 36 healthy volunteers; this gives them the rate of absorption, or bioavailability, of the generic drug, which they can then compare to that of the innovator drug”. Making the chemical is cheap. If you also want FDA approval, it costs $2 million and takes two years. There’s also the problem of how pharmacies and insurance companies price things. It’s an interesting read.
  • Timing of Medicines. I mentioned blood pressure meds above. Here’s an interesting note related to that: taking your blood pressure meds before bed instead of in the morning lowers your diabetes risk. In one study, when adjusted for age, waist circumference, glucose, chronic kidney disease, and hypertension treatment the researchers found sleeping blood pressure was the most significant predictor of diabetes risk, while waking blood pressure was found to have no predictive value. A second study found, when accounting for age, waist circumference, glucose, chronic kidney disease and specific treatment, that taking the blood pressure medications at night resulted in a 57 percent decrease in the risk of developing diabetes.
  • Male Birth Controls. A new approach has been found towards a possible male birth control pill. This approach doesn’t focus on hormones, but proteins. A study in mice focused on a protein called calcineurin, which is found in the sperm-producing cells of the testes as well as other cells in the body. The researchers genetically engineered mice so that they lacked a gene that makes part of the calcineurin protein but is activated only in sperm-producing cells. When these mice had sex, they were infertile, the researchers said. When the researchers tried to figure out why their genetically engineered mice were infertile, they found that the mice’s sperm cells did not swim well and were not able to fertilize eggs. Further experiments found that the midpieces of these sperm didn’t bend normally, which prevented the sperm from penetrating the membrane of an egg. Now to see if this works with humans.
  • Ringing in the Ears. One side effect of my migraines is tinitus — what some call “ringing” in the ears, but which (for me) is a high-pitched squeal. For the longest time, we didn’t know what caused it…. but now we do. It turns out it shares a common source with chronic pain. Doctors compared tinnitus patients with those who did not have tinnitus and found volume loss in the medial prefrontal cortex, an area that plays a role in the limbic system and functions as a “gate” or control area for noise and pain signals that is also associated with depression. This is an area that also lights up when you play unpleasant noises, so it has to do with unpleasant sensations. They found the ventromedial prefrontal cortex and the nucleus accumbens are part of a “gatekeeping” system that determines which sounds or other stimuli to admit. When the system is defective, affected patients can be subjected to constant stimuli and long-lasting disturbances. The area is also associated with depression and anxiety, conditions often arise “in lockstep” with chronic pain. Because of this, the researchers are now looking to drugs that regulate that system, like dopamine and serotonin, to restore the gatekeeping role and eliminate the chronic pain, but more research is needed.
  • Eliminating Plastics. One of the scourges of the model world is plastic. Very useful, it is also not biodegradable and becomes the waste that will list forever. But then again… it turns out the mealworms and mealmoth larvae eat plastic and generate biodegradable poop from it. This explains how they get into food wrapped in plastic.  Being serious: Larvae of the darkling beetle will not only feed on expanded polystyrene, but microorganisms in their guts biodegrade it internally. And then, they poop out a seemingly safe product that may be suitable as soil for crops. Another surprise is that the PS doesn’t seem to be toxic to the insects. This work is building on research initiated at the Beihang University in China, where researchers observed waxworms, the larvae of Indian mealmoths, break down polyethylene in the form of plastic bags thanks to microorganisms in their guts. So far, the excreted waste appears safe to use as soil.
  • Picking a Boy/Girlfriend. Ever wonder why you don’t think your best friend’s partner is cute? Ever wonder why you think your love is beautiful, but no one else does? Science has figured out why.  According to a new study, it’s our life experiences—not a perfectly chiseled jaw or sultry bedroom eyes—that make a person’s face appealing to us. Sure, symmetrical features are generally more attractive than non-symmetrical ones, but an even face only partially accounts for someone’s overall “attractiveness,” researchers find. Physical attraction is highly personal—even among relations who’ve had similar upbringings. Researchers chalked up the differences to our own distinct life experiences, which can vary widely thanks to co-workers, peers, past relationships, and media exposure. Essentially, if you’ve had good experiences with people who have certain facial characteristics, you’ll most likely find them attractive. As time passes, others who look like them will seem good-looking to you as well.

 

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Saturday News Chum Stew: Theatre Etiquette, Water, Fat, Cybersecurity, and Science

Observation StewIt’s Saturday, and it’s been a busy couple of weeks. Time to clean out the accumulated links. Before I do, however, here’s a reminder link: If you are a Windows user and comtemplating upgrading to Windows 10, you should read my summary post about why I’m waiting, and what I want to remember when I finally do. On to the stew:

 

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Saturday News Chum: Pools, Morticians, Vinyl, Plutonium, and Facebook

Observation StewIt’s an oddly stormy July day here in Southern California (a bit worrisome because I have outdoor theatre tickets tonight). Still, storms make it a perfect time for some stew. I’ve also got two other themed articles brewing on the back burners (one on food, and one on cybersecurity), but the haven’t quite set up right yet. So let’s dig into the stew:

  • Benefitting from the Drought. Having a pool is a headache. You’ve got to keep it full; you’ve got to keep it clean. Additionally, when there is a drought, you worry about the water lost to evaporation… and leaks. Further, if you have a leak, think of the water bill if you have to drain and refill it to repair. I’m telling you this because some niche businesses benefit from a drought: In particular, a pool repair man who is able to repair pools under water has more work than he can handle. He’s developed a pool repair compound (trade secret) that can be applied and cure under water, meaning that pools do not require draining for repair. I found this very interesting, as I suspect my pool to have another leak… and for that leak to be somewhere deep where I can’t find it. During the summer, it is hard to differentiate water lost to a leak from water lost to evaporation.
  • No One Ever Plans to Be A Mortician. This is one of my favorite phrases… and so here’s an article about morticians. Specifically, it is about two Los Angeles morticians who are trying to effect a radical shakeup of the undertaking business. What they want to do is return death to the home. In other words, people are removed from death and their loved ones. People used to die at home; now they die in hospitals. They are handled in isolation by undertakers, who pump them full of chemicals to make them look alive. These two young morticians work with families to facilitate what the two call a “more natural” death — no formaldehyde cocktail, no pods that fill hollow eyes, no mouth former, no satin-lined casket, no metal vault. The goal is to promote home funerals. If family members care to, they can undress, bathe, and cool the body with ice themselves or they can watch them do so. Interesting concept.
  • The Rebirth of Vinyl. If you purchase music these days, you’ve probably heard about the rebirth of vinyl records; quite suprising in this day of digital music and CDs. But not everyone thinks it will last. In particular, Noel Paul Stookey, of Peter Paul and Mary, thinks the current resurgence of vinyl is just a fad. Specifically, he thinks a trend to oversampling will eliminate the sound advantage, but the tactile and emotional advantage will remain. Then again, if you don’t have a place or way to listen to the music you own, what difference does it make.
  • Invisible Girlfriends. On the Internet, there’s a service for everything — even being an invisible girlfriend who is there only in text messages. This service is provided in a way similar to a Mechanical Turk: it is crowdsourced. What is it like to be an Invisible Girlfriend? Funny you should ask: Someone wrote an article about the experience. This seems the perfect subject for a Reply All episode.
  • Magnets and Plutonium. Pluto has been in the news, so why not Plutonium. Plutonium is an odd metal: based on where it is in the periodic table, one would expect it to be magnetic — yet it isn’t. Scientists have just started to figure out why. The reason is that plutonium can have four, five or six electrons in the outer shell in the ground state (they previously thought the number was fixed); further, not only does it fluctuate between the three different configurations, it is in all three at the same time. Because the number of electrons in plutonium’s outer shell keeps changing, the unpaired electrons in the outer shell can never line up in a magnetic field and so plutonium can’t become magnetic.
  • Taking Control of Your Digital Life. One of the things that was nice about Livejournal was the ability to see what was happening with your friends chronologically, back to the point where you had last done so. Facebook and their algorithms made that difficult: you were never sure if you were seeing everything from everyone — Facebook tried to bring up what it thought was most important. That all may be changing. Supposedly, Facebook is going to soon let you bypass their algorithm. After years of sorting news feeds primarily by algorithm, Facebook is letting users choose what they want to see first.An update to Facebook’s iOS app expands the existing “News Feed Preferences” section with a way to choose whose updates appear at the top of the timeline. A similar update is coming to Facebook’s Android app and desktop website in the coming weeks. Users can check out the new settings by pressing the “More” button in the Facebook app’s bottom-right corner, then tapping on “News Feed Preferences” and selecting “Prioritize who to see first.” This brings up a list of friends and Pages that users can mark as favorites. Unread updates from favorite contacts will always appear at the top of the News Feed, overriding Facebook’s predictive algorithms.

That’s it — your stew for the weekend. Let’s now hope that the storm (we’ve got thunder and rain as I type this) doesn’t cancel tonight’s theatre. Update: It did 🙁

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You Are What You Eat

userpic=gluten-freeHere are a few posts from the last few weeks related to what you eat, and its effects. This is timely, as the CDF Food Fair and Convention is this weekend.

 

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Something To Stew About

Observation StewThis has been another busy week, what with trying to get the truth out about the kerfluffle at the REP in Santa Clarita (#IStandWithTheREP),  my daughter Erin being in town getting ready to go off to a summer Yiddish program back east, installing and setting up a new password manager, and loads of stuff at work. Still, I grabbed a few articles of interest:

 

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